VERBI VEnice Research BIbliography

Il dato di concentrazione per ciascuna sostanza è stato convertito in concentrazione equivalente di estradiolo, EEQ, mediante i fattori di equivalenza dell’estradiolo, EEF, in modo da determinare la potenza estrogenica totale nelle matrici ambientali acqua e sedimento. Da dati di letteratura, i valori di EEQ ottenuti per i campioni acquosi (2.8-191 ng/L, media: 28 ng/L) e per i sedimenti (4.7-190 µg/Kg, media: 69 µg/kg), con il preponderante contributo delle sostanze naturali e di sintesi steroidee (> 99.9%) per le acque, e quello delle sostanze di sintesi steroidee e non (> 99%) per i sedimenti, possono causare effetti negativi sugli organismi acquatici.

The exposure to estrogenic substances both natural (estradiol, estrone and estriol) and synthetic (ethinylestradiol, mestranol, nonylphenol, octylphenol, nonylphenol monoethoxylate carboxylate, benzophenone, bisphenol-A, diethylstilbestrol) in the Venice lagoon (Italy) was assessed by means of Solid Phase Extraction followed by High Performance Liquid Chromatography separation coupled with Ion Trap – Mass Spectrometry detection via Electrospray Interface (SPE-HPLC-ESI-IT-MS).

The individual compound concentrations were converted into estradiol equivalent concentration (EEQ), by means of estradiol equivalency factors (EEF), in order to estimate the estrogenic potency of Venice lagoon water and sediment. According to literature, EEQ found for the aqueous samples (2.8-191 ng/L, average: 28 ng/L) and for the sediment samples (4.7-190 µg/Kg, media: 69 µg/kg), are likely to pose adverse effects on the Venice aquatic wildlife.